Transvestites are typically men who like to dress up as women. It doesn't necessarily mean these men wish they were women or that they are gay - it's just something they like to do.
For the sake of discussion: transsexual and transgender mean the same thing.
Can people who have this disorder ever feel comfortable as their biological gender?
I could be wrong, but I don't view this as a disorder, that is, if you speak of the disorder in the sense that it's a mental disorder. Not sure why, I just have trouble accepting it in those terms.
We assume that it can be treated and that it's as simple as environmental trauma, but are we right? We say that about homosexuality as well, but even with extensive counseling and hormonal treatment, people continue their lives with deep internal struggle.
To "we", as a society, that are not specifically going through what these individuals (both transgender and homosexual), it may seem it as something to be treated - but I don't think that's accurate. I believe transgenders are born this way - there was some sort of hormonal mix-up or something when they were being made. And I believe that hormones are not something that can be couseled away - medicated, possibly, but with the involvement of the brain and any developments within that, it could make it more difficult to "counsel away".
Let's take for example a very basic issue, that most people would not associate with hormones and one that I have experience with: wetting the bed. My father did it, I did it, my little sister did it - well into our childhood years (I'm talking until I was 10 or 11, maybe even sporadically after that). My little sister and I tried everything so we wouldn't wet the bed at night - ranging from working/strengthening muscles in that region, not drinking anything 2 to 3 hours before going to bed, going to the restroom just before bed then having our parents wake us up to go to the restroom again when they were going to bed. We tried beepers that would wake us up if it detected anything happening. All this was to no avail. It wasn't until I was 10 that the doctors were able to determine that my wetting the bed was a result of an underdeveloped hormone. I started taking nasal spray every night before bed as a hormone additive or replacement (I don't know exactly what) - and this pretty much stopped me wetting the bed. I eventually grew out of it because my hormone eventually developed - but this was something I grew up with and had to deal with - no sleep overs, no over night summer camps, etc. because I would always wet the bed and end up embarassing myself. My issue was something that was able to be treated because it wasn't a missing hormone, it was just a deficient one that eventually fully developed over time.
Now what I believe about transgenders is that they were born with something missing, not something that was underdeveloped, etc. And I believe you could only immitate that missing hormone, or whatever, for a period of time before it is eventually realized this treatment is only prolonging the inevitable and hiding who these people truly are. You can't counsel away nature.
I'm not sure how I feel about homosexuals - some may be born that way as evidenced in the way they act as children, while others may choose this path down the road (as evidenced by people being married for 30 years and realizing that they are happier with people of the same sex - I have seen this happen to one of my friends parents). This is an entirely different topic though from the one at hand, and therefore I will not delve into it.